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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) (), a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the human body, constituting twenty-eight percent of total CYPs in the human body.

CYP3A4Cytochrome P450CYP3A7Pregnane X receptorGrapefruitAtorvastatinGrapefruit drug interactionsStatinTerfenadineCYP3ACarbamazepineDiltiazemSynergistic enhancer (antiretroviral)DextromethorphanErythromycin breath testErythromycinTicagrelorTabimorelinSertralineRitonavir
Amentoflavone3-MethoxymorphinanMethadoneOmeprazoleAprepitantCilostazolLurasidoneCyproteroneSimvastatinLovastatinKetamineClonazepamChloramphenicolReboxetinePrimidoneDofetilideUlipristal acetateGrapefruit juiceSolifenacinGuanfacine

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